Vioxx Information

Generic Name: rofecoxib (oral) (row feh COCK sib)
Brand Names: Vioxx

What's the most important information I should find out about Vioxx?

Vioxx was withdrawn from the U.S. market in 2004.

The producer of Vioxx has announced a voluntary withdrawal of the drug from the U.S. and worldwide market. This withdrawal is because of safety considerations of an increased threat of cardiovascular events (together with coronary heart assault and stroke) in sufferers taking Vioxx.

Notify your doctor instantly should you develop abdominal ache, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a pores and skin rash; itching; yellowing of your skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous aspect effects.

What's Vioxx?

Vioxx was withdrawn from the U.S. market in 2004.

Vioxx is in a class of medicine called nonsteroidal anti-inflammatory medicine (NSAIDs). Vioxx works by lowering substances that cause inflammation, pain, and fever in the body.

Vioxx is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and sure forms of juvenile rheumatoid arthritis; to handle acute ache in adults; to deal with migraines; and to treat menstrual pain.

Vioxx may be used for functions other than those listed on this remedy guide.

What should I focus on with my healthcare provider before taking Vioxx?

The producer of Vioxx has introduced a voluntary withdrawal of the drug from the U.S. and worldwide market. This withdrawal is because of safety considerations of an elevated risk of cardiovascular occasions (including heart attack and stroke) in patients taking Vioxx.

Don't take Vioxx with out first speaking to your physician in case you have skilled bronchial asthma, hives, or an allergic reaction after taking aspirin or another NSAID reminiscent of ibuprofen (Motrin, Advil, Nuprin), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), celecoxib (Celebrex), valdecoxib (Bextra), or meloxicam (Mobic). It's possible you'll expertise an identical response to Vioxx.
Before taking Vioxx, tell your doctor when you
  • smoke;
  • drink alcohol;
  • have ever had an ulcer or bleeding in your stomach;
  • have liver illness;
  • have kidney disease;
  • have bronchial asthma;
  • have congestive heart failure;
  • have fluid retention;
  • have coronary heart illness;
  • have hypertension;
  • have a coagulation (bleeding) dysfunction or are taking an anticoagulant (blood thinner) such as warfarin (Coumadin); or
  • are taking a steroid medication reminiscent of prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others.
You could not be able to take Vioxx, or you might require a dosage adjustment or special monitoring during therapy if in case you have any of the conditions, or are taking any of the medicines, listed above.

Vioxx is within the FDA being pregnant class C. Because of this it is not known whether it would harm an unborn baby. Vioxx should not be taken late in being pregnant (the third trimester) as a result of it could have an effect on the formation of the newborn's heart. Don't take Vioxx with out first talking to your doctor if you are pregnant or could become pregnant throughout treatment. It is not identified whether Vioxx passes into breast milk. Don't take Vioxx without first speaking to your doctor if you're breast-feeding. In case you are over the age of 65 years, you could be more more likely to expertise negative effects from Vioxx. You could require a decrease dosage or special monitoring during treatment.

How should I take Vioxx?

Take Vioxx precisely as directed by your doctor. If you don't understand these instructions, ask your pharmacist, nurse, or physician to explain them to you.

Take every dose with a full glass of water. Shake the Vioxx suspension properly before measuring a dose. Use a dose-measuring cup or spoon, not a daily table spoon, to measure the liquid form of Vioxx to ensure that you measure the right amount of medicine. If you don't have a dose-measuring gadget, ask your pharmacist where you can get one.
Vioxx can be taken with or without food or milk.

Retailer Vioxx at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as quickly as you remember. If it is almost time for the following dose, skip the dose you missed and take only the subsequent frequently scheduled dose as directed. Do not take a double dose of this medication until your doctor directs otherwise.

What occurs if I overdose?

Search emergency medical attention.
Symptoms of a Vioxx overdose are usually not known.

What should I avoid whereas taking Vioxx?

There are not any restrictions on meals, drinks, or activity during remedy with Vioxx, unless in any other case directed by your doctor.

What are the possible side effects of Vioxx?

Notify your doctor immediately in the event you develop abdominal pain, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight acquire; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of your skin or eyes;"flu-like" signs; or uncommon bruising or bleeding. These symptoms could possibly be early signs of dangerous side effects.

Should you expertise any of the next severe unintended effects, cease taking Vioxx and seek medical remedy or contact your doctor instantly:
  • an allergic response (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • stomach pain, tenderness, or discomfort;
  • bloody, black, or tarry stools;
  • nausea or heartburn;
  • blood in your vomit;
  • unexplained weight gain;
  • swelling or water retention;
  • unusual fatigue or lethargy;
  • a pores and skin rash or itching;
  • yellowing of your skin or eyes;
  • "flu-like" signs; or
  • unusual bruising or bleeding.
Different, less serious side effects could also be more likely to occur. Continue to take Vioxx and speak to your physician should you experience
  • dizziness;
  • mild fatigue or weak point; or
  • diarrhea.
Unintended effects aside from those listed right here may occur. Discuss to your physician about any facet effect that appears uncommon or that is particularly bothersome.

What other medication will affect Vioxx?

 Before taking Vioxx, tell your doctor if you are taking any of the following drugs:
  • aspirin or an aspirin-like treatment akin to salsalate (Disalcid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, Bayer Select Backache Method, others);
  • an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen;
  • a diuretic (water capsule) resembling furosemide (Lasix), hydrochlorothiazide (Hydrodiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Hygroton, Thalitone), and others;
  • an angiotensin-changing-enzyme inhibitor (ACE inhibitor) resembling benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), and others;
  • a steroid drugs comparable to prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others;
  • an anticoagulant (blood thinner) such as warfarin (Coumadin);
  • methotrexate (Rheumatrex, Folex);
  • theophylline (Theo-Dur, Theobid, and others);
  • lithium (Eskalith, Lithobid, others); or
  • rifampin (Rimactane, Rifadin, Rifater).
Chances are you'll not be capable to take an Vioxx, or you might require a dosage adjustment or special monitoring throughout therapy if you are taking any of the medicines listed above.

Medicine aside from those listed right here may additionally interact with Vioxx. Discuss to your doctor and pharmacist before taking any prescription or over-the-counter medicines, together with natural products.

Where can I get extra data?

Your pharmacist has further details about Vioxx written for health professionals that you could be read.

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