Tramadol Information

Generic Name: tramadol (TRAM a dol)
Brand names: Rybix ODT, Ryzolt, Ultram, Ultram ER

What is tramadol?

Tramadol is a narcotic-like pain reliever.

Tramadol is used to treat moderate to extreme pain. Tramadol extended-release is used to treat reasonable to extreme persistent pain when treatment is needed across the clock.

Tramadol might also be used for other functions not listed in this medication guide.

Essential details about tramadol

You should not take this medication in case you are allergic to tramadol, in case you have ever been addicted to medicine or alcohol, or when you have ever attempted suicide. Don't take tramadol while you're intoxicated (drunk) or taking any of the following: alcohol or avenue medication, narcotic pain medicine, sedatives or tranquilizers, or drugs for despair, anxiety, or psychological illness.

Seizures (convulsions) have occurred in some folks taking this medicine. Tramadol could also be more more likely to trigger a seizure when you have a historical past of seizures or head injury, a metabolic disorder, or if you are taking sure medicines resembling antidepressants, muscle relaxers, narcotic, or drugs for nausea and vomiting.

Seek emergency medical consideration for those who think you've gotten used an excessive amount of of this medicine. A tramadol overdose might be fatal.

Tramadol could also be behavior-forming. Inform your doctor if you happen to feel the medicine just isn't working as well in relieving your pain. By no means share tramadol with one other particular person, particularly someone with a historical past of drug abuse or addiction. Keep the medication in a spot the place others cannot get to it.

Do not crush the tramadol tablet. This drugs is for oral (by mouth) use only. Powder from a crushed pill should not be inhaled or diluted with liquid and injected into the body. Using this medication by inhalation or injection may cause life-threatening unintended effects, overdose, or death.

Before taking tramadol

You shouldn't take this remedy if you're allergic to tramadol, when you have ever been addicted to drugs or alcohol, or if you have ever tried suicide.

Do not take tramadol when you are intoxicated (drunk) or taking any of the next:

•     alcohol or avenue medicine;
•     narcotic ache medication;
•     sedatives or tranquilizers (akin to Valium);
•     drugs for despair or anxiety; or
•     drugs for mental sickness (corresponding to bipolar disorder, schizophrenia).

Seizures have occurred in some individuals taking tramadol. Talk with your physician about your seizure danger, which can be greater when you've got:

•     a history of drug or alcohol addiction;
•     a historical past of epilepsy or different seizure dysfunction;
•     a historical past of head damage;
•     a metabolic disorder; or
•     in case you are also taking an antidepressant, muscle relaxer, narcotic, antipsychotic, or medication for nausea and vomiting.

To ensure you can safely take tramadol, inform your doctor if you have any of those other circumstances:

•     kidney illness (or if you're on dialysis);
•     cirrhosis or other liver disease;
•     a abdomen dysfunction; or
•     a historical past of despair, psychological illness, or ideas of suicide.

FDA pregnancy category C. It is not known whether or not tramadol will hurt an unborn baby. Tramadol may cause serious or deadly side effects in a newborn if the mom makes use of this medication throughout being pregnant or labor. Tell your doctor if you are pregnant or plan to develop into pregnant whereas using this medication. Tramadol can move into breast milk and should harm a nursing baby. You should not breast-feed while you're taking tramadol. Don't give this remedy to anyone youthful than 16 years previous without the advice of a doctor.

How should I take tramadol?

Take tramadol exactly as prescribed. By no means take tramadol in bigger amounts, or for longer than beneficial by your doctor. Observe the instructions on your prescription label. Inform your physician if the drugs seems to stop working as nicely in relieving your pain.

Tramadol may be taken with or with out food, but take it the same way every time.

Don't crush, chew, or break a tramadol tablet. Swallow it whole. Breaking the tablet might cause too much of the drug to be released at one time. This medication is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this drugs by inhalation or injection can cause life-threatening unintended effects, overdose, or death.

To take tramadol orally disintegrating tablets (Rybix ODT):

•     Hold the tablet in its blister pack till you are ready to take it.
•     Using dry palms, remove the pill and place it in your mouth. It is going to start to dissolve right away.
•     Don't swallow the tablet whole. Permit it to dissolve in your mouth with out chewing.
•     Swallow several times as the pill dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Should you use the tramadol extended-launch tablet, the pill shell could pass into your stools (bowel movements). This is regular and does not mean that you're not receiving enough of the medicine.

Tramadol may be habit-forming. Never share tramadol with another particular person, particularly somebody with a history of drug abuse or addiction. Don't stop utilizing tramadol out of the blue, or you can have disagreeable withdrawal symptoms. Discuss to your doctor about methods to avoid withdrawal signs when stopping the medication.

Store tramadol at room temperature away from moisture and heat. Keep monitor of the amount of medicine used from each new bottle. Tramadol is a drug of abuse and you ought to be conscious if anyone is using your medication improperly or with out a prescription.

What occurs if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose whether it is almost time for your next scheduled dose. Don't take further medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical consideration or name the Poison Assist line at 1-800-222-1222. A tramadol overdose may be fatal.

Overdose symptoms might include extreme drowsiness, shallow respiratory, muscle weakness, sluggish heartbeat, chilly or clammy skin, fainting, or seizure.

What should I avoid when taking tramadol?

Do not drink alcohol. It may trigger a dangerous lower in your respiration when used along with this medicine. Tramadol could impair your pondering or reactions. Be careful when you drive or do anything that requires you to be alert.

Tramadol side effects

Get emergency medical assist if in case you have any of these signs of an allergic response to tramadol: hives; problem respiration; swelling of your face, lips, tongue, or throat. Cease using tramadol and name your doctor at once if in case you have any of these severe unwanted effects:

•     agitation, hallucinations, fever, fast coronary heart fee, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
•     seizure (convulsions);
•     a pink, blistering, peeling pores and skin rash; or
•     shallow breathing, weak pulse.

Much less serious tramadol unwanted effects might embrace:

•     dizziness, spinning sensation;
•     constipation, upset abdomen;
•     headache;
•     drowsiness; or
•     feeling nervous or anxious.

This isn't a whole checklist of unwanted effects and others may occur. Call your physician for medical recommendation about side effects. Chances are you'll report negative effects to FDA at 1-800-FDA-1088.

Tramadol Dosing Data

Typical Grownup Tramadol Dose for Ache:

For gentle to average extreme chronic ache not requiring rapid onset of analgesic effect:
Initial dose: 25 mg each morning
Titration: increase in 25 mg increments as separate doses each three days to reach a hundred mg per day taken as 25 mg four occasions per day. Then the overall daily dose may be elevated by 50 mg as tolerated every three days to succeed in 200 mg per day taken as 50 mg four instances per day.
Maintenance: After titration, tramadol 50 mg to one hundred mg can be administered as needed for ache reduction each four to six hours to not exceed 400 mg per day.

For the management of reasonable to reasonably severe  power pain in adults who require around-the-clock therapy of their pain for an prolonged time period:
Prolonged-Launch Tablets:
Preliminary Dose: one hundred mg as soon as day by day and titrated up as obligatory by one hundred mg increments every five days to reduction of pain and relying upon tolerability.
Maximum Dose: Extended-launch tablets shouldn't be administered at a dose exceeding 300 mg per day.

For patients in whom rapid onset of analgesic effect is required and for whom the benefits outweigh the risk of discontinuation resulting from opposed events associated with larger preliminary dose:
Dose: 50 mg to one hundred mg could be administered as wanted for ache reduction each 4 to 6 hours, to not exceed four hundred mg per day.

Ordinary Geriatric Tramadol Dose for Pain:

For sufferers over 65 years:
Dose choice ought to be cautious, often beginning at the low finish of the dosing vary, reflecting the larger frequency of decreased hepatic, renal, or cardiac perform and of concomitant illness or other drug therapy.

For sufferers over 75 years:
Maximum dose of regular oral tablets: 300 mg per day in divided doses

Ordinary Pediatric Tramadol Dose for Pain:

16 years outdated and up:
Brand title: Ryzolt
Preliminary: one hundred mg once every day
Titrate by 100 mg increments every 2 to three days if wanted for ache management
Maximum: 300 mg/day

What other medication will have an effect on tramadol?

You might be extra more likely to have a seizure (convulsions) if you take tramadol if you are using sure different medicines. Do not take tramadol with out telling your physician in the event you additionally use any of the following drugs:

•     an MAO inhibitor akin to isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
•     an antidepressant resembling amitriptyline (Elavil, Vanatrip), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft).

Cold or allergy medication, sleeping drugs, muscle relaxers, and medication for seizures or anxiousness can add to sleepiness brought on by tramadol. Tell your physician in the event you commonly use any of those medicines, or some other ache medication.

Inform your physician about all other medicines you employ, particularly:

•     carbamazepine (Tegretol);
•     lithium (Eskalith, LithoBid);
•     ADHD medications (Adderall, Ritalin, Strattera);
•     an antibiotic resembling clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), linezolid (Zyvox), rifampin (Rifadin, Rimactane, Rifater); or telithromycin (Ketek);
•     antifungal medicine equivalent to clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);
•     most cancers medicines such as gefitinib (Iressa), imatinib (Gleevec), or nilotinib (Tasigna);
•     a heart rhythm treatment comparable to amiodarone (Cordarone, Pacerone), flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quin-G);
•     coronary heart or blood strain treatment comparable to diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;
•     HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir, Kaletra); or
•     migraine headache drugs similar to sumatriptan (Imitrex, Treximet).

This checklist just isn't full and there are lots of other drugs that can interact with tramadol. Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new treatment without telling your doctor. Keep a listing of all of your medicines and present it to any healthcare supplier who treats you.

Where can I get more information?

    Your pharmacist can provide more information about tramadol.

    Every effort has been made to make sure that the information provided is correct, up-to-date, and complete, however no assure is made to that effect. Drug information contained herein could also be time sensitive. Multum's drug info is an informational useful resource designed to help licensed well beingcare practitioners in caring for his or her patients and/or to serve shoppers viewing this service as a supplement to, and never a substitute for, the experience, ability, data and judgment of well beingcare practitioners. The absence of a warning for a given drug or drug mixture in no way should be construed to point that the drug or drug combination is secure, effective or applicable for any given patient. The data contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or hostile effects.