Vioxx Information

Generic Name: rofecoxib (oral) (row feh COCK sib)
Brand Names: Vioxx

What's the most important information I should find out about Vioxx?

Vioxx was withdrawn from the U.S. market in 2004.

The producer of Vioxx has announced a voluntary withdrawal of the drug from the U.S. and worldwide market. This withdrawal is because of safety considerations of an increased threat of cardiovascular events (together with coronary heart assault and stroke) in sufferers taking Vioxx.

Notify your doctor instantly should you develop abdominal ache, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a pores and skin rash; itching; yellowing of your skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous aspect effects.

What's Vioxx?

Vioxx was withdrawn from the U.S. market in 2004.

Vioxx is in a class of medicine called nonsteroidal anti-inflammatory medicine (NSAIDs). Vioxx works by lowering substances that cause inflammation, pain, and fever in the body.

Vioxx is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and sure forms of juvenile rheumatoid arthritis; to handle acute ache in adults; to deal with migraines; and to treat menstrual pain.

Vioxx may be used for functions other than those listed on this remedy guide.

What should I focus on with my healthcare provider before taking Vioxx?

The producer of Vioxx has introduced a voluntary withdrawal of the drug from the U.S. and worldwide market. This withdrawal is because of safety considerations of an elevated risk of cardiovascular occasions (including heart attack and stroke) in patients taking Vioxx.

Don't take Vioxx with out first speaking to your physician in case you have skilled bronchial asthma, hives, or an allergic reaction after taking aspirin or another NSAID reminiscent of ibuprofen (Motrin, Advil, Nuprin), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), celecoxib (Celebrex), valdecoxib (Bextra), or meloxicam (Mobic). It's possible you'll expertise an identical response to Vioxx.
Before taking Vioxx, tell your doctor when you
  • smoke;
  • drink alcohol;
  • have ever had an ulcer or bleeding in your stomach;
  • have liver illness;
  • have kidney disease;
  • have bronchial asthma;
  • have congestive heart failure;
  • have fluid retention;
  • have coronary heart illness;
  • have hypertension;
  • have a coagulation (bleeding) dysfunction or are taking an anticoagulant (blood thinner) such as warfarin (Coumadin); or
  • are taking a steroid medication reminiscent of prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others.
You could not be able to take Vioxx, or you might require a dosage adjustment or special monitoring during therapy if in case you have any of the conditions, or are taking any of the medicines, listed above.

Vioxx is within the FDA being pregnant class C. Because of this it is not known whether it would harm an unborn baby. Vioxx should not be taken late in being pregnant (the third trimester) as a result of it could have an effect on the formation of the newborn's heart. Don't take Vioxx with out first talking to your doctor if you are pregnant or could become pregnant throughout treatment. It is not identified whether Vioxx passes into breast milk. Don't take Vioxx without first speaking to your doctor if you're breast-feeding. In case you are over the age of 65 years, you could be more more likely to expertise negative effects from Vioxx. You could require a decrease dosage or special monitoring during treatment.

How should I take Vioxx?

Take Vioxx precisely as directed by your doctor. If you don't understand these instructions, ask your pharmacist, nurse, or physician to explain them to you.

Take every dose with a full glass of water. Shake the Vioxx suspension properly before measuring a dose. Use a dose-measuring cup or spoon, not a daily table spoon, to measure the liquid form of Vioxx to ensure that you measure the right amount of medicine. If you don't have a dose-measuring gadget, ask your pharmacist where you can get one.
Vioxx can be taken with or without food or milk.

Retailer Vioxx at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as quickly as you remember. If it is almost time for the following dose, skip the dose you missed and take only the subsequent frequently scheduled dose as directed. Do not take a double dose of this medication until your doctor directs otherwise.

What occurs if I overdose?

Search emergency medical attention.
Symptoms of a Vioxx overdose are usually not known.

What should I avoid whereas taking Vioxx?

There are not any restrictions on meals, drinks, or activity during remedy with Vioxx, unless in any other case directed by your doctor.

What are the possible side effects of Vioxx?

Notify your doctor immediately in the event you develop abdominal pain, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight acquire; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of your skin or eyes;"flu-like" signs; or uncommon bruising or bleeding. These symptoms could possibly be early signs of dangerous side effects.

Should you expertise any of the next severe unintended effects, cease taking Vioxx and seek medical remedy or contact your doctor instantly:
  • an allergic response (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • stomach pain, tenderness, or discomfort;
  • bloody, black, or tarry stools;
  • nausea or heartburn;
  • blood in your vomit;
  • unexplained weight gain;
  • swelling or water retention;
  • unusual fatigue or lethargy;
  • a pores and skin rash or itching;
  • yellowing of your skin or eyes;
  • "flu-like" signs; or
  • unusual bruising or bleeding.
Different, less serious side effects could also be more likely to occur. Continue to take Vioxx and speak to your physician should you experience
  • dizziness;
  • mild fatigue or weak point; or
  • diarrhea.
Unintended effects aside from those listed right here may occur. Discuss to your physician about any facet effect that appears uncommon or that is particularly bothersome.

What other medication will affect Vioxx?

 Before taking Vioxx, tell your doctor if you are taking any of the following drugs:
  • aspirin or an aspirin-like treatment akin to salsalate (Disalcid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, Bayer Select Backache Method, others);
  • an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen;
  • a diuretic (water capsule) resembling furosemide (Lasix), hydrochlorothiazide (Hydrodiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Hygroton, Thalitone), and others;
  • an angiotensin-changing-enzyme inhibitor (ACE inhibitor) resembling benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), and others;
  • a steroid drugs comparable to prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others;
  • an anticoagulant (blood thinner) such as warfarin (Coumadin);
  • methotrexate (Rheumatrex, Folex);
  • theophylline (Theo-Dur, Theobid, and others);
  • lithium (Eskalith, Lithobid, others); or
  • rifampin (Rimactane, Rifadin, Rifater).
Chances are you'll not be capable to take an Vioxx, or you might require a dosage adjustment or special monitoring throughout therapy if you are taking any of the medicines listed above.

Medicine aside from those listed right here may additionally interact with Vioxx. Discuss to your doctor and pharmacist before taking any prescription or over-the-counter medicines, together with natural products.

Where can I get extra data?

Your pharmacist has further details about Vioxx written for health professionals that you could be read.

Voltaren Information


Generic Name: diclofenac (dye KLOE fen ak)
Brand Names: Cambia, Cataflam, Voltaren, Voltaren-XR, Zipsor

What is Voltaren?

Voltaren (diclofenac) is a non steroidal anti inflammatory drug (NSAID). This drugs works by decreasing substances within the body that cause ache inflammation.

Voltaren is used to treat pain or inflammation brought on by rheumatoid arthritis, osteoarthritis or ankylosing spondylitis.

Voltaren may be used for purposes not listed in this medicine guide.

Important information about Voltaren

Voltaren may cause life-threatening heart or circulation issues comparable to coronary heart assault or stroke, especially should you use it long term. Don't use Voltaren just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Get emergency medical assist when you have chest pain, weakness, shortness of breath, slurred speech, or issues with vision or balance.

Voltaren might also trigger severe effects on the abdomen or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can happen without warning if you are taking Voltaren, especially in older adults.

Call your doctor without delay in case you have signs of abdomen bleeding akin to black, bloody, or tarry stools, or coughing up blood or vomit that appears like espresso grounds.

Ask a health care provider or pharmacist before utilizing any cold, allergy, or other pain medicine. Medicines much like diclofenac are contained in lots of combination medicines. Taking certain products collectively can trigger you to get too much of such a medication. Examine the label to see if a medicine incorporates aspirin, ibuprofen, ketoprofen, or naproxen. Avoid drinking alcohol. It might improve your risk of abdomen bleeding.

Before taking Voltaren

Don't use Voltaren simply before or after coronary heart bypass surgery (coronary artery bypass graft, or CABG).

Voltaren may trigger life-threatening heart or circulation issues such as heart assault or stroke, particularly if you happen to use it long term.

This drugs may additionally trigger critical results on the stomach or intestines, including bleeding or perforation (forming of a hole). These circumstances can be deadly and can happen with out warning while you are taking Voltaren, particularly in older adults.

You should not use Voltaren in case you are allergic to diclofenac, or if you have a history of allergic response to aspirin or other NSAIDs.

To ensure you can safely take Voltaren, tell your doctor when you have any of those different conditions:
  • a historical past of heart assault, stroke, or blood clot;
  • heart illness, congestive coronary heart failure, high blood pressure;
  • a history of abdomen ulcers or bleeding;
  • liver or kidney disease,
  • bronchial asthma;
  • polyps in your nostril;
  • a bleeding or blood clotting disorder; or
  • if you smoke.
FDA being pregnant class D. Tell your doctor in case you are pregnant or plan to develop into pregnant throughout treatment. Taking Voltaren over the last 3 months of being pregnant could hurt the unborn baby. Don't take Voltaren throughout being pregnant unless your physician has instructed you to. It's not recognized whether or not diclofenac passes into breast milk or if it may harm a nursing baby. You should not breast-feed while you are using Voltaren. Do not give this drugs to a baby younger than 18 years old without medical advice.

How should I take Voltaren?

Take Voltaren exactly as prescribed by your doctor. Don't take in bigger or smaller quantities or for longer than recommended. Observe the directions on your prescription label.

If you change brands of diclofenac, your dose needs could change. Observe your physician's directions about how much drugs to take.

Don't crush, chew, or break a Voltaren extended-launch tablet. Swallow it whole. Breaking the tablet may cause too much of the drug to be released at one time.

Don't crush, chew, or break a Voltaren enteric-coated tablet. Swallow the pill whole. The enteric-coated tablet has a special coating to protect your stomach. Breaking the tablet may injury this coating.

Should you use Voltaren lengthy-term, your liver function will have to be checked with frequent blood tests. Go to your doctor regularly.

Store Voltaren at room temperature away from moisture and heat.

What occurs if I miss a dose?

Take the missed dose as quickly as you remember. Skip the missed dose whether it is almost time in your subsequent scheduled dose. Do not take additional medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or name the Poison Help line at 1-800-222-1222.

Overdose symptoms might include nausea, vomiting, abdomen pain, drowsiness, black or bloody stools, coughing up blood, shallow respiratory, and fainting.

What should I keep away from when taking Voltaren?

Ask a doctor or pharmacist before using any chilly, allergy, or different ache medicine. Medicines similar to diclofenac are contained in many mixture medicines. Taking sure products together can cause you to get too much of this type of medication. Examine the label to see if a medicine incorporates aspirin, ibuprofen, ketoprofen, or naproxen.

Keep away from ingesting alcohol. It may improve your risk of abdomen bleeding. Keep away from exposure to daylight or tanning beds. Voltaren can make you sunburn extra easily. Put on protecting clothes and use sunscreen (SPF 30 or greater) when you find yourself outdoors.

Voltaren unwanted effects

Get emergency medical help if in case you have any of these indicators of an allergic reaction to Voltaren: hives; difficulty respiratory; swelling of your face, lips, tongue, or throat. Stop using Voltaren and call your physician without delay if you have a severe aspect impact comparable to:
  • chest ache, weakness, shortness of breath, slurred speech, problems with imaginative and prescient or stability;
  • black, bloody, or tarry stools;
  • coughing up blood or vomit that appears like espresso grounds;
  • swelling or speedy weight achieve, urinating lower than ordinary or under no circumstances;
  • nausea, upper stomach pain, itching, loss of appetite, darkish urine, clay-colored stools, jaundice (yellowing of the pores and skin or eyes);
  • bruising, severe tingling, numbness, pain, muscle weak point;
  • neck stiffness, chills, increased sensitivity to light, purple spots on the pores and skin, and/or seizure (convulsions); or
  • extreme pores and skin response -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin ache, followed by a pink or purple pores and skin rash that spreads (particularly in the face or higher physique) and causes blistering and peeling.
Much less severe Voltaren uncomfortable side effects might embody:
  • upset stomach, delicate heartburn or abdomen ache, diarrhea, constipation bloating, fuel;
  • dizziness, headache, nervousness;
  • pores and skin itching or rash;
  • blurred vision; or
  • ringing in your ears.
This isn't a complete list of side effects and others may occur. Name your doctor for medical recommendation about aspect effects. Chances are you'll report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Voltaren?

Ask your physician before utilizing an antidepressant equivalent to citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking any of those medicines with an NSAID may trigger you to bruise or bleed easily.

Inform your physician about all different drugs you use, particularly:
  • a blood thinner corresponding to warfarin (Coumadin, Jantoven);
  • cyclosporine (Gengraf, Neoral, Sandimmune);
  • isoniazid (for treating tuberculosis);
  • lithium (Eskalith, Lithobid);
  • methotrexate (Rheumatrex, Trexall);
  • pronbenecid (Benemid);
  • rifampin (Rifadin, Rifater, Rifamate);
  • secobarbital (Seconal);
  • sertraline (Zoloft);
  • sulfamethoxazole (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);
  • teniposide (Vumon);
  • zafirlukast (Accolate);
  • a diuretic (water capsule) akin to furosemide (Lasix).
  • steroids (prednisone and others);
  • antifungal medicine such as fluconazole (Diflucan) or voriconazole (Vfend);
  • aspirin or other NSAIDs (non-steroidal anti-inflammatory medicine) akin to ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), indomethacin (Indocin), meloxicam (Mobic), and others;
  • cholesterol-reducing medicine reminiscent of fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, TriCor, Triglide), fluvastatin (Lescol), or lovastatin (Mevacor, Altoprev, Advicor); or
  • heart or blood pressure medication resembling amiodarone (Cordarone, Pacerone), benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others.
This checklist is not full and other drugs could interact with Voltaren. Inform your physician about all drugs you use. This includes prescription, over-the-counter, vitamin, and natural products. Don't start a new treatment with out telling your doctor.

Where can I get more info?

Your pharmacist can provide more details about Voltaren.

Vytorin Information

Generic Name: ezetimibe and simvastatin (ez ET i mibe and SIM va stat in)
Brand Names: Vytorin

What is Vytorin?

Vytorin contains a combination of ezetimibe and simvastatin.

Vytorin is used to treat excessive ldl cholesterol in adults and children who're no less than 10 years old.

Ezetimibe reduces the quantity of cholesterol absorbed by the body.

Simvastatin is in a bunch of drugs known as HMG CoA reductase inhibitors, or "statins." Simvastatin reduces ranges of "dangerous" ldl cholesterol (low-density lipoprotein, or LDL) and triglycerides within the blood, whereas increasing ranges of "good" cholesterol (high-density lipoprotein, or HDL).

Vytorin may additionally be used for functions not listed in this remedy guide.

Vital information about Vytorin

You should not take Vytorin if you are allergic to ezetimibe and simvastatin, if you have liver disease, or if you are pregnant or breast-feeding. In uncommon cases, simvastatin can trigger a situation that ends in the breakdown of skeletal muscle tissue, leading to kidney failure. Name your doctor right away when you've got unexplained muscle pain, tenderness, or weak point especially in case you even have fever, uncommon tiredness, and dark coloured urine.

Never take Vytorin in bigger quantities, or for longer than really useful by your doctor. Observe your physician's dosing directions very carefully. Taking too much Vytorin may cause severe or life-threatening facet effects.

There are lots of different drugs that should not be used along with Vytorin. Tell your doctor about all drugs you use. Hold an inventory of all your medicines and present it to any healthcare supplier who treats you.

Before taking Vytorin, tell your doctor in case you have ever had liver or kidney disease, diabetes, or a thyroid dysfunction, if you are of Chinese language descent, or when you drink greater than 2 alcoholic drinks daily.

Vytorin can harm an unborn baby or trigger delivery defects. Don't use if you are pregnant.

Grapefruit and grapefruit juice could work together with simvastatin and lead to probably dangerous effects. Don't drink more than 1 quart of grapefruit juice daily.

Before taking Vytorin

You should not take Vytorin if you're allergic to ezetimibe or simvastatin, if you have liver disease, or if you are pregnant or breast-feeding. In rare circumstances, simvastatin can cause a condition that leads to the breakdown of skeletal muscle tissue, resulting in kidney failure. This situation could also be extra more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid). You might also be extra prone to develop this situation in case you are of Chinese descent and you're taking high-dose Vytorin whereas additionally taking medicine that contains niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others).

The following drugs can improve your danger of great muscle issues if you happen to take them together with simvastatin. These medicine should not be used if you are taking Vytorin:
  • cyclosporine (Gengraf, Neoral, Sandimmune);
  • danazol (Danocrine);
  • gemfibrozil (Lopid);
  • nefazodone (an antidepressant);
  • the antibiotics clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), and telithromycin (Ketek);
  • the antifungal drugs itraconazole (Sporanox), ketoconazole (Nizoral), and posaconazole (Noxafil); or
  • the HIV/AIDS medications atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), saquinavir (Invirase), and tipranavir (Aptivus).
Before you start taking Vytorin, inform your doctor in case you are already using any of those different medicines:
  • amiodarone (Cordarone, Pacerone);
  • amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide);
  • diltiazem (Cartia, Cardizem);
  • ranolazine (Ranexa); or
  • verapamil (Calan, Covera, Isoptin, Verelan).
To ensure you can safely take Vytorin, inform your doctor if you have any of those other situations:
  • history of liver illness;
  • historical past of kidney disease;
  • diabetes;
  • a thyroid dysfunction; or
  • for those who drink more than 2 alcoholic beverages daily.
FDA being pregnant category X. Vytorin can harm an unborn child or trigger delivery defects. Don't take Vytorin if you're pregnant. Cease taking this treatment and inform your physician right away should you develop into pregnant. Use effective contraception to avoid pregnancy while you're taking Vytorin. Ezetimibe and simvastatin could move into breast milk and will harm a nursing baby. Don't breast-feed while you are taking Vytorin.

How should I take Vytorin?

Take Vytorin exactly as prescribed. By no means take this medication in bigger quantities, or for longer than advisable by your doctor. Follow your physician's dosing directions very carefully. Taking too much of Vytorin could trigger critical or life-threatening aspect effects.

Vytorin is normally taken as soon as every day within the night, with or with out food. Your doctor might sometimes change your dose to ensure you get the best results.

To be sure Vytorin helps your situation and isn't causing harmful effects, your blood will should be tested often. Your liver perform should be examined each three to six months. Visit your physician regularly. It's possible you'll have to take Vytorin on a long-time period foundation for the remedy of high cholesterol. It's possible you'll need to cease using Vytorin for a short while when you have surgical procedure or a medical emergency. Don't cease taking Vytorin until your doctor tells you to.

Vytorin is just a part of an entire program of treatment that additionally includes weight loss plan, exercise, and weight control. Observe your weight loss program, remedy, and exercise routines very closely.

Store Vytorin at room temperature away from moisture and heat. Hold the bottle tightly closed when not in use.

What occurs if I miss a dose?

Take the missed dose as quickly as you remember. Skip the missed dose whether it is virtually time on your subsequent scheduled dose. Don't take further medication to make up the missed dose.

What occurs if I overdose?

Search emergency medical attention or name the Poison Help line at 1-800-222-1222.

What should I keep away from while taking Vytorin?

Grapefruit and grapefruit juice may interact with simvastatin and result in potentially dangerous effects. Don't drink more than 1 quart of grapefruit juice daily.

For those who additionally take cholestyramine (Prevalite, Questran) or colestipol (Colestid), avoid taking them inside 2 hours after or four hours before you're taking Vytorin.

Avoid eating meals which can be excessive in fat or cholesterol. Vytorin will not be as efficient in lowering your cholesterol if you don't observe a ldl cholesterol-reducing weight loss plan plan.

Keep away from ingesting alcohol. It can raise triglyceride levels and should improve your threat of liver damage.

Vytorin uncomfortable side effects

Get emergency medical help you probably have any of these indicators of an allergic response to Vytorin: hives; issue respiratory; swelling of your face, lips, tongue, or throat.

Stop taking Vytorin and name your physician at once when you've got any of those severe unwanted side effects:
  • unexplained muscle pain, tenderness, or weak spot;
  • fever, unusual tiredness, and darkish coloured urine;
  • swelling, weight acquire, urinating less than ordinary or by no means;
  • chest ache, dry cough, wheezing, feeling wanting breath;
  • severe ache in your higher abdomen spreading to your back, nausea and vomiting, quick heart price; or
  • nausea, upper abdomen ache, itching, loss of urge for food, darkish urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Much less severe Vytorin negative effects may embody:
  • headache, reminiscence problems, dizziness, depressed mood;
  • again pain, joint ache, gentle muscle ache;
  • numbness or tingly feeling;
  • trouble having an erection;
  • diarrhea;
  • sleep issues (insomnia); or
  • chilly symptoms resembling stuffy nostril, sneezing, sore throat.
This isn't an entire checklist of unintended effects and others might occur. Call your doctor for medical advice about aspect effects. You could report unwanted side effects to FDA at 1-800-FDA-1088.

What other medication will have an effect on Vytorin?

Inform your doctor about all other medicines you employ, particularly:
  • colchicine (Colcrys);
  • digoxin (Lanoxin);
  • a blood thinner akin to warfarin (Coumadin, Jantoven);
  • fenofibric acid (Fibricor, Trilipix), or fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, Tricor, Triglide);
  • antifungal drugs reminiscent of fluconazole (Diflucan) or voriconazole (Vfend);
  • medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
  • medication that weaken your immune system, such as steroids, cancer medicine, or medicines used to stop organ transplant rejection, equivalent to sirolimus (Rapamune), or tacrolimus (Prograf); or
  • any other "statin" treatment resembling atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), or different medication that incorporates simvastatin (Simcor, Zocor).
This record will not be full and there are lots of different medication that can cause severe or life threatening medical issues should you take them along with Vytorin. Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your doctor. Preserve a listing of all your medicines and show it to any healthcare provider who treats you.

Where can I get extra information?

Your pharmacist can present extra details about Vytorin.

Wellbutrin Information

Generic Name: bupropion (byoo PRO pee on)
Brand Names: Aplenzin, Budeprion, Wellbutrin, Zyban

What is Wellbutrin?

Wellbutrin (bupropion) is an antidepressant medication. It works within the mind to deal with depression.

Wellbutrin is used to treat major depressive disorder and seasonal affective disorder. No less than one model of bupropion (Zyban) is used to help individuals stop smoking by lowering cravings and other withdrawal effects.

Wellbutrin may additionally be used for different functions not listed on this medication guide.

Important details about Wellbutrin

Don't take Wellbutrin if you have taken a monoamine oxidase inhibitor (MAOI) similar to furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the final 14 days. You should not take Wellbutrin if you have seizures, an consuming disorder, if you're utilizing a second type of bupropion, or when you have abruptly stopped using alcohol or sedatives.

Wellbutrin may trigger seizures, especially in folks with certain medical situations or when using certain drugs. Tell your physician about all your medical situations and the medicine you use.

You might have thoughts about suicide once you first begin taking an antidepressant resembling Wellbutrin, particularly in case you are youthful than 24 years old. Your physician will need to check you at common visits for at the very least the first 12 weeks of treatment.

Report any new or worsening signs to your physician, resembling: temper or conduct changes, nervousness, panic assaults, hassle sleeping, or in case you feel impulsive, irritable, agitated, hostile, aggressive, stressed, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Avoid drinking alcohol whereas taking Wellbutrin. It could enhance your danger of seizures.

Before taking Wellbutrin

Do not take Wellbutrin if you have taken a monoamine oxidase inhibitor (MAOI) equivalent to furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) within the last 14 days.

You should not take Wellbutrin if in case you have:
  • epilepsy or a seizure disorder;
  • an eating disorder akin to anorexia or bulimia;
  • if you are utilizing a second form of bupropion; or
  • in case you have instantly stopped utilizing alcohol or sedatives (resembling Valium).
Wellbutrin might cause seizures, particularly in folks with sure medical conditions. Tell your physician about your entire medical conditions.

If in case you have any of these different circumstances, your physician might have to regulate your Wellbutrin dosage or order particular assessments:
  • a historical past of head harm, seizures, or mind or spinal wire tumor;
  • coronary heart illness, hypertension, history of heart assault;
  • kidney illness;
  • liver disease (especially cirrhosis); or
  • bipolar dysfunction (manic despair).
You might have ideas about suicide if you first begin taking an antidepressant equivalent to Wellbutrin, especially in case you are youthful than 24 years old. Tell your doctor in case you have worsening symptoms of despair or suicidal ideas in the course of the first a number of weeks of remedy, or every time your dose is changed.

Your family or other caregivers should even be alert to adjustments in your mood or symptoms. Your physician will need to check you at regular visits for at the least the first 12 weeks of remedy with Wellbutrin.

FDA pregnancy class C. It isn't known whether or not Wellbutrin will harm an unborn baby. Tell your doctor if you are pregnant or plan to develop into pregnant whereas utilizing Wellbutrin. Bupropion passes into breast milk and could be harmful to a nursing baby. You should not breast-feed when you are taking Wellbutrin.

How should I take Wellbutrin?

Take Wellbutrin exactly as prescribed by your doctor. Do not soak up larger or smaller quantities or for longer than recommended. Follow the directions in your prescription label.

Your doctor might occasionally change your dose to be sure to get the best results.

Wellbutrin can be taken with or with out food.

Don't crush, chew, or break an extended-launch tablet. Swallow it whole. Breaking the capsule could cause too much of the drug to be launched at one time, which might enhance unwanted effects together with seizures.

Don't cease taking Wellbutrin without first talking to your doctor. You'll have unpleasant unintended effects in case you cease taking this treatment suddenly.

Should you use the Wellbutrin prolonged-release tablet, the pill shell might pass into your stools (bowel actions). That is regular and doesn't imply that you are not receiving enough of the medicine.

Wellbutrin can trigger you to have a false constructive drug screening test. Should you present a urine pattern for drug screening, inform the laboratory workers that you are taking bupropion.

Store Wellbutrin at room temperature away from moisture and heat.

What occurs if I miss a dose?

Take the missed dose as quickly as you remember. Skip the missed dose if it is virtually time to your next scheduled dose. Don't take additional drugs to make up the missed dose.

What occurs if I overdose?

Search emergency medical consideration or name the Poison Assist line at 1-800-222-1222. An overdose of Wellbutrin can be fatal. Overdose symptoms may embody muscle stiffness, hallucinations, quick or uneven heartbeat, shallow respiratory, or fainting.

What should I avoid while taking Wellbutrin?

Drinking alcohol may increase your risk of seizures. In case you drink alcohol regularly, talk with your physician before altering the quantity you drink. Wellbutrin can trigger seizures in individuals who drink plenty of alcohol and then all of the sudden stop consuming once they begin using the medication.

Avoid utilizing bupropion to deal with multiple condition at a time. If you take Wellbutrin for despair, do not also take Zyban to quit smoking. Too much of this medicine can increase your threat of a seizure.

Wellbutrin could impair your considering or reactions. Be careful if you drive or do anything that requires you to be alert.

Wellbutrin side effects

Get emergency medical help when you've got any of these indicators of an allergic reaction to Wellbutrin: hives; difficulty respiratory; swelling of your face, lips, tongue, or throat.

Report any new or worsening signs to your doctor, resembling: temper or habits changes, anxiety, panic assaults, trouble sleeping, or for those who feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), extra depressed, or have thoughts about suicide or hurting yourself.

Call your physician without delay you probably have a severe facet impact while taking Wellbutrin resembling:
  • seizure (convulsions);
  • extreme blistering, peeling, and pink skin rash;
  • fever, swollen glands, rash or itching, joint pain, or general ill feeling;
  • confusion, bother concentrating; or
  • hallucinations, uncommon ideas or behavior.
Much less serious Wellbutrin negative effects could embody:
  • headache or migraine;
  • sleep problems (insomnia);
  • nausea, vomiting, constipation, dry mouth;
  • dizziness, tremors (shaking);
  • urge for food adjustments, weight loss or acquire;
  • mild itching or skin rash, elevated sweating; or
  • lack of interest in sex.
This is not a complete listing of uncomfortable side effects and others may occur. Call your doctor for medical advice about facet effects. You may report side effects to FDA at 1-800-FDA-1088.

Wellbutrin Dosing Information

Standard Grownup Wellbutrin Dose for Melancholy:

Rapid release tablets:
Preliminary dose: a hundred mg orally twice a day.
Upkeep dose: The dosage could also be increased in 75 to 100 mg/day increments no more usually than each 3 days up to the standard upkeep dose of a hundred mg orally three instances a day. The maximum dose is 450 mg/day, given in 4 divided doses; Wellbutrin should be discontinued if there may be not an ample response to this dose. Single doses should not exceed one hundred fifty mg.

Sustained release tablets:
Preliminary dose: 150 mg orally as soon as a day within the morning.
Upkeep dose: After not less than 4 days, the dose may be increased to a hundred to a hundred and fifty mg twice a day. If there is not satisfactory improvement after a number of weeks, the dose could also be elevated to a maximum of 200 mg twice a day.

Extended release tablets (Wellbutrin XL):
Initial dose: a hundred and fifty mg orally once a day in the morning.
Maintenance dose: After at least four days, the dose could also be increased to 300 mg once a day. If there is not adequate improvement after a number of weeks, the dose may be increased to a most of 450 mg as soon as a day in the morning.

Typical Grownup Wellbutrin Dose for Seasonal Affective Dysfunction:

Extended-release:
Initial: one hundred fifty mg orally once a day in the morning
Titration: If tolerated, after 7 days dose may be elevated to maximum dose of four hundred mg as soon as a day administered in the morning. Sufferers who're unable to tolerate this increase in dose should be lowered again to a hundred and fifty mg orally once a day.

Ordinary Geriatric Dose for Melancholy:

Preliminary dose: seventy five mg orally twice a day.
Upkeep dose: seventy five mg orally 3 times a day.
Maximum doses:
Immediate Release: a hundred and fifty mg orally 3 times a day.
Sustained Launch: four hundred mg given as 200 mg twice a day.

Common Pediatric Wellbutrin Dose for Consideration Deficit Dysfunction:

Rapid release tablets:
6 to 18 years:
20 to 30 kg: 50 to a hundred and fifty mg/day in 2 divided doses (investigational).
31 to forty kg: seventy five to 200 mg/day in 2 divided doses (investigational).
Higher than 40 kg: 100 to 250 mg/day in 2 divided doses (investigational).

Extended launch tablets:
Less than 11 years: Security and effectiveness haven't been established.
11 to 18 years: a hundred and fifty to 300 mg/day in 2 divided doses (investigational).

What other drugs will affect Wellbutrin?

Many medicine can work together with Wellbutrin. Below is just a partial list. Inform your physician in case you are using:
  • treatment used to prevent blood clots, such as clopidogrel (Plavix) or ticlopidine (Ticlid), tirofiban (Aggrastat);
  • cancer drugs such as cyclophosphamide (Cytoxan, Neosar), doxorubicin (Adriamycin, Doxil), irinotecan (Camptosar), or thiotepa (Thioplex);
  • heart or blood strain remedy similar to atenolol (Tenormin), flecainide (Tambocor), metoprolol (Lopressor, Toprol), propafenone (Rythmol), propranolol (Inderal), and others; or
  • HIV or AIDS medication such as efavirenz (Atripla, Sustiva) or ritonavir (Norvir, Kaletra).
This list just isn't full and there are a lot of different medicine that can interact with Wellbutrin. Inform your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a brand new medicine without telling your doctor. Hold a listing of all your medicines and present it to any healthcare provider who treats you. You might have a better threat of seizures if you use sure medications along with Wellbutrin. Tell your physician about all other drugs you use, especially:
  • any other antidepressant, or a medication to deal with a psychiatric disorder;
  • antihistamines that make you sleepy;
  • asthma drugs or bronchodilators;
  • contraception tablets or hormone substitute estrogens;
  • bladder or urinary drugs resembling oxybutynin (Ditropan, Urotrol);
  • antibiotics reminiscent of cefdinir (Omnicef), cephalexin (Keflex), ciprofloxacin (Cipro), amoxicillin (Amoxil, Augmentin), penicillin, and others;
  • fat burners, a stimulant, or ADHD treatment similar to Adderall or Ritalin;
  • insulin or diabetes medications you take by mouth;
  • medicine for nausea, vomiting, or movement sickness;
  • drugs to deal with or prevent malaria;
  • medicines to treat Parkinson's illness, restless leg syndrome, or pituitary gland tumor (prolactinoma);
  • medicines used to forestall organ transplant rejection;
  • narcotic pain remedy;
  • a sedative similar to diazepam (Valium), and others;
  • a steroid equivalent to prednisone, and others;
  • avenue drugs akin to "velocity" or cocaine;
  • theophylline (Theo-Dur, Slo-Bid, Bronkodyl Theolair, Respbid); or
  • ulcer or irritable bowel medications.
Where can I get extra info?

Your pharmacist can present extra information about Wellbutrin.